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Neurovascular Unit and the Role of Astrocytes in the Regulation of Vascular Tone

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Neurovascular Unit and the Role of Astrocytes in the Regulation of Vascular Tone

Reviews the cellular mechanisms contributing to astrocyte-mediated vasodilation and vasoconstriction of parenchymal arterioles. Primarily, the authors discuss how activity-dependent changes in astrocytic Ca2+ contribute to the release of vasoactive signals involved in neurovascular coupling.
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